For the second straight season, the NFL will feature a Friday night game in Sao Paulo, Brazil, in the Week 1 NFL schedule. For the 2025 NFL season, the Kansas City Chiefs will face the Los Angeles Chargers from Brazil in an AFC West showdown. The Chiefs are looking to erase the memory of their 40-22 loss to the Eagles in the Super Bowl after playing in their fifth Super Bowl over the last six years. The Chargers made the postseason in Year 1 of the Jim Harbaugh era, but lost to the Texans, 32-12, in the Wild Card round. Kickoff is set for 8 p.m. ET on Friday from Neo Química Arena in São Paulo, Brazil.
There are dozens of betting options if you’re wondering how to bet on the NFL, or more specifically, Chargers vs. Chiefs. Here’s a closer look at available sportsbook promos on some of the top NFL betting sites, as well as the best betting apps that are available for Chiefs vs. Chargers on Friday, with instructions on how to claim each offer and where to bet NFL.
Where to bet on Chiefs vs. Chargers on Friday
The DraftKings promo code, bet365 bonus code and FanDuel promo code all offer bonus bets after new users place a wager of $5 or more. bet365 is offering new users either $300 in bonus bets with the placement of a $5+ bet, or up to a $1,000 first bet safety net. DraftKings is giving new users $300 in bonus bets after new users bet at least $5 with their first wager, in addition to more than $200 off NFL Sunday Ticket. At FanDuel, new users can claim $300 in bonus bets if their first bet of at least $5 wins.
Both the BetMGM bonus code and Fanatics Sportsbook promo code provide bonus bets, but only if your first bet loses. New users at Fanatics have the ability to get 20+ $100 No Sweat Bets in FanCash if your first football bet loses on every Game Day from now until Oct. 12. Meanwhile, the BetMGM bonus code CBSSPORTS awards new users up to $1,500 back in bonus bets if their first bet loses. BetMGM users in New Jersey, West Virginia, Pennsylvania or Michigan can get a different promotion and receive $150 in bonus bets if you win your first bet of $10 or more.
The Caesars Sportsbook promo code is different than the aforementioned offers, providing profit boosts instead of bonus bets. At Caesars, new users can get 20 100% sportsbook profit boosts with a $1 bet.
Bettors can use any of these promotions for Chargers vs. Chiefs on Friday, September 5.
Chiefs vs. Chargers betting preview, picks
Chargers (+3) vs. Chiefs
The Chargers played the Chiefs tough in both of their matchups last season, but Kansas City won both via 17-10 and 19-17 finals. Kansas City won’t have its full complement of playmakers, however, with wide receiver Rashee Rice opening the 2025 NFL season with a six-game suspension. The Chiefs are coming off an 18-point loss in the Super Bowl last season, and since 2000, Super Bowl losers are 11-14 straight-up and 6-19 against the spread in their season opener. Since 1990, 11 teams have lost in the Super Bowl by more than 14 points, and they went 4-7 straight-up and 2-9 ATS in their season openers, showing some form of a Super Bowl hangover. This bodes well for the Chargers, who are returning stars like Justin Herbert and Ladd McConkey, as underdogs. The model projects the Chargers to cover in 50% of simulations.
Under 45.5 total points
The Chiefs and Chargers went Under this total in each of their contests last season, combining for 27 points and 36 points in their divisional matchups. Both teams had one of the best defenses in the NFL last season, and that’s not expected to change this fall. The Chargers ranked second at 18.5 points per game allowed, and the Chiefs were sixth at 20.5 ppg allowed. The Chargers held Patrick Mahomes to fewer than 250 passing yards in both games, and without Rice at receiver, the Los Angeles secondary could challenge Mahomes again. The model projects the Under to hit in 60% of simulations.
Responsible gaming
Responsible gaming is a serious topic, and all sportsbooks take steps to ensure users play responsibly. The top sportsbooks feature several tools and resources available on their apps and websites, including wager limits, voluntary self-exclusion options, and more. If you or someone you know is dealing with a gambling problem, please seek assistance from trained professionals such as the Problem Gambling Help Network at 1-800-GAMBLER.
